Giant Lipid Vesicles, topologically closed cell-sized compartments isolating pico- to femto-liter quantities of the aqueous phase, are bounded by highly flexible and semi-permeable quasi-two dimensional membrane. When immersed in a hypertonic bath, the efflux of water (but not the solute) from the compartment drives dramatic shape transitions, which recapitulate many a shape transition in living cells. Prof. Parikh co-authored an invited feature article in the March issue of Langmuir on the subject of Giant Lipid Vesicles. Read the article at http://pubs.acs.org/doi/abs/10.1021/acs.langmuir.5b04470.
Mixing Water, Transducing Energy, Shaping Membranes: Autonomously Self-regulating Giant Vesicles, James Ho C. S., Padmini Rangamani, Bo Liedberg, Atul N. Parikh Langmuir 32, 2151–2163, 2016.