Environmental Scanning Electron Microscopy


Quattro S
The first of its kind in the U.S., the Quattro S allows researchers to explore and image with nanometer resolution nearly any material on earth, from extremely hard materials to living cellular structures. (Alexander Fisher-Wagner/UC Davis)

The ThermoFisher Quattro S is an environmental scanning electron microscope (SEM) equipped with a Schottky field electron gun. It is capable of operating at pressures up to 50 mbar. The large pressure range allows the user to acquire images of hydrated specimens. The low vacuum regime also enables users to take images of non-conducting samples without coating them with gold or carbon. The instrument is equipped with various in-situ accessories for heating, cooling, and hardness testing with a nanoindenter. A Bruker XFlash detector is attached for chemical characterization over a 100 mm² area. 

The acquisition of the ThermoFisher Quattro S SEM and the nanoindenter was funded by a National Science Foundation Major Research Instrumentation grant, MRI-1725618 (PI: Klaus van Benthem, Co-PIs: Gang-Yu Liu, Nitin Nitin, Srabanti Chowdhury, and Paul Fitzgerald)   


  • Accelerating voltage: 200 V-30 kV
  • Spatial resolution: <1.0 nm at 30 kV
  • Working distance: 2 to 14 mm
  • Maximum sample size: 122 mm diameter
  • Maximum sample height: 10 mm
  • Working pressure: 1x10⁻⁶ mbar to 50 mbar


  • Everhart Thornley Detector (SE, BSE)
  • Retractable Annular and Circular Backscatter Detector (SE, BSE)
  • Retractable Annular STEM (TE)
  • In-column Electron Detector (SE)
  • Low Vacuum Detector (SE)
  • Gaseous Secondary Electron Detector (SE)
  • Gaseous Analytical Detector (BSE)
In-situ Accessories
  • WetSTEM Stage (-25°C to 55°C)
  • Heating Stage 1000 (40°C to 1000°C)
  • Heating Stage 1400 (200°C to 1400°C)
  • Nanomechanics InSEM Nanoindenter (up to 50 mN)
  • Bruker XFlash 6|100 EDS Detector


108 Kemper Hall

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